Table 1.
Characteristics of patients with HIV mono‐infection under long‐term ART
| All (n = 395) | |
|---|---|
| Social and demographic characteristics | |
| Female gendera | 236 (60) |
| Age, yearsb | 45 [35 to 52] |
| Black/Brown racea | 210 (53) |
| Probable route of HIV acquisitiona | |
| Heterosexual women | 191 (48) |
| Men who have sex with men | 101 (26) |
| Heterosexual men | 44 (11) |
| Other | 22 (6) |
| Missing | 37 (9) |
| Education level <8 years of studya | 193 (49) |
| AUDIT score ≥8a | 90 (23) |
| Former or current smokinga | 184 (47) |
| Metabolic features | |
| BMI, kg/m²b | 25.7 [23.2 to 29.4] |
| Central obesity (wc ≥ 90 cm in men and ≥80 cm in women)a | 266 (68) |
| Type 2 diabetesa | 37 (10) |
| Dyslipidaemiaa | 234 (61) |
| Hypertensiona | 118 (30) |
| Metabolic syndromea | 117 (32) |
| Biochemistry | |
| ALT, IU/Lb | 30 [23 to 42] |
| AST, IU/Lb | 26 [20 to 34] |
| GGT, IU/Lb | 46 [34 to 76] |
| Alkaline phosphatase, IU/Lb | 88 [69 to 107] |
| Total bilirubin, mg/dLb | 0.43 [0.30 to 0.77] |
| Albumin, mg/dLb | 3.9 [3.7 to 4.1] |
| Fasting glucose, mg/dLb | 93 [87 to 100] |
| Triglycerides, mg/dLb | 127 [87 to 178] |
| Total cholesterol, mg/dLb | 185 [155 to 219] |
| LDL‐cholesterol, mg/dLb | 112 [88 to 138] |
| HDL‐cholesterol, mg/dLb | 42 [35 to 54] |
| HIV infection and ART history | |
| Duration of HIV infection, yearsb | 10 [6 to 16] |
| CD4+ T‐lymphocyte count (cells/mm3)b | 667 [427 to 906] |
| CD4+ T‐lymphocyte count <200 cells/mm3 a | 17 (5) |
| Detectable HIV RNA viral load (>40 copies/mm3)a | 80 (20) |
| Nadir CD4+ T‐lymphocyte count <100 cells/mm3)a | 104 (26) |
| Duration of ART, yearsb | 7 [4 to 14] |
| Current ART | |
| TDF‐backbone drugsa/AZT‐backbone drugsa | 309 (78)/86 (22) |
| Core drugs treatment by NNRTIa/PI or INSTIa | 175 (44)/220 (56) |
| Most used ART | |
| TDF‐backbone drugsa/AZT‐backbone drugsa | 225 (57)/170 (43) |
| Core drugs treatment by NNRTIa/PI or INSTIa | 197 (50)/198 (50) |
Other probable routes for HIV infection: vertical transmission (n = 7), transfusion of blood products (n = 10), injected drug users (n = 3), occupational accident (n = 2).
ALT, alanine aminotransferase; ART, antiretroviral therapy; AST, aspartate aminotransferase; AUDIT, Alcohol Use Disorders Identification Test; AZT, zidovudine; BMI, body mass index; GGT, gamma‐glutamyltransferase; HDL, high‐density lipoprotein; INSTI, integrase strand transfer inhibitors; LDL, low‐density lipoprotein; NNRTI, non‐nucleoside reverse‐transcriptase inhibitors; PI, protease inhibitor, TDF, tenofovir; wc, waist circumference.
Data expressed as aabsolute (%) or bmedian [IQR].