Skip to main content
. 2018 Sep 20;7(11):829–838. doi: 10.1002/sctm.18-0009

Figure 4.

Figure 4

Representative micrographs of brain slices stained for TH. Compared to the sham group (A, F), all the animals that were submitted to 6‐OHDA injection presented a reduction of TH expression levels. However, animals injected with (D, I) hNPCs CM (i.e., secretome) had significantly more TH‐positive staining when compared to the (B, G) 6‐OHDA untreated group, both in (E) SNpc and (J) striatum. Data are presented as mean ±SEM. *p ≤ .05; Sham animals statistically different from all the other groups: #, p ≤ .0001. (Scale bar: 2000 μm). Abbreviations: 6‐OHDA, 6‐hydroxidopamine; hNPCs, human neural progenitor cells; hNPCs‐CM, human neural progenitor cells‐conditioned media; SNpc, substantia nigra pars compacta; TH, tyrosine hydroxylase.