Table 5. GRS in GERA and UKB ethnicity groups.

		P (426 SNPs)	P+G+GG (457 SNPs)	P+G+GG	P+G+GG	P+G+GG	P+G+GG
Group	Sex	R2	R2	Mean	SD	Eff.	P
GERA non-Hispanic whites	F	0.032	0.035	7.632	0.265	0.772	10−374
GERA non-Hispanic whites	M	0.030	0.032	6.776	0.248	0.612	10−244
GERA Latinos	F	0.039	0.041	7.604	0.257	0.856	10−48
GERA Latinos	M	0.028	0.028	6.746	0.239	0.600	10−22
GERA East Asians	F	0.024	0.026	7.340	0.243	0.689	10−26
GERA East Asians	M	0.015	0.017	6.536	0.212	0.573	10−12
GERA African Americans	F	0.015	0.020	7.606	0.229	0.666	10−9
GERA African Americans	M	0.012	0.013	6.699	0.212	0.466	10−4
UKB non-Hispanic whites	F	0.027	0.030	8.315	0.287	0.639	10−1545
UKB non-Hispanic whites	M	0.030	0.033	6.017	0.217	0.760	10−1451
UKB mixed/other	F	0.033	0.035	8.346	0.288	0.700	10−34
UKB mixed/other	M	0.029	0.032	5.956	0.217	0.748	10−26
UKB East Asians	F	0.017	0.020	8.184	0.251	0.571	10−6
UKB East Asians	M	0.016	0.014	5.864	0.190	0.599	10−3
UKB African British	F	0.013	0.013	8.554	0.245	0.524	10−15
UKB African British	M	0.018	0.015	5.818	0.179	0.573	10−13
UKB South Asians	F	0.018	0.019	8.289	0.269	0.567	10−19
UKB South Asians	M	0.022	0.021	5.928	0.207	0.624	10−24

Abbreviations: P, previously-identified; G, GERA-identified; GG, GERA+GIANT-identified; R², variance explained from GRS using GERA meta-analysis effect sizes (stratified by sex); Eff., effect; GERA, Genetic Epidemiology Research on Adult Health and Aging cohort; GIANT, Genetic Investigation of Anthropomorphic Traits consortium; UKB, UK Biobank.