Figure A6.
The LASSO algorithm is used to construct a predictor from the most significant GIANT SNPs, nearly all of which can be found among UKBB imputed SNPs. UKBB phenotypes are used as before. The specific predictor used for this graph achieves a correlation of 0.59. GIANT P-values of SNPs are displayed on the x-axis, and the average individual variance explained by SNPs within each of 1000 bins is computed and displayed on the y-axis.