Table 3.
Bivariate analysis (provides unadjusted ORs)
| Presenting symptoms and risk factors | OR (95% CI) | p value |
|---|---|---|
| Decreased level of consciousness | 5.76 (2.60–12.77) | <0.0001* |
| Initial Glasgow Coma Scale score | 4.83 (2.11–11.05) | 0.0002* |
| Papilledema | 4.52 (1.55–13.19) | 0.006* |
| Altered mental status | 3.96 (1.80–8.71) | 0.001* |
| Bilateral transverse sinus thrombosis | 3.45 (1.25–9.49) | 0.02* |
| Seizure activity | 3.18 (1.23–8.26) | 0.02* |
| Unilateral internal jugular thrombosis | 2.19 (0.94–5.09) | 0.07 |
| Ischemic infarct on neuroimages | 2.19 (0.89–5.42) | 0.09 |
| Bleeding on initial neuroimages | 1.83 (0.86–3.90) | 0.12 |
| Location score (number of sinuses involved) | 1.35 (1.03–1.76) | 0.03* |
| Nausea/vomiting | 1.34 (0.64–2.84) | 0.44 |
| Focal weakness | 1.34 (0.57–3.14) | 0.51 |
| Cortical vein thrombosis | 1.31 (0.38–4.52) | 0.68 |
| Superior sagittal sinus thrombosis | 1.26 (0.58–2.70) | 0.56 |
| Elevated total bilirubin | 1.12 (0.87–1.44) | 0.38 |
| Unilateral sagittal sinus thrombosis | 1.12 (0.51–2.42) | 0.78 |
| Elevated potassium | 1.02 (0.95–1.10) | 0.60 |
| Elevated creatinine | 1.01 (0.62–1.64) | 0.98 |
| Protein S deficiency | 1.00 (1.00–1.02) | 0.84 |
| Platelet count | 1.00 (0.99–1.00) | 0.13 |
| Elevated blood urea nitrogen | 1.00 (0.97–1.02) | 0.74 |
| Elevated lactate | 0.99 (0.77–1.28) | 0.95 |
| Deep venous sinus thrombosis | 0.95 (0.24–3.72) | 0.94 |
| Sodium level | 0.92 (0.82–1.03) | 0.16 |
| Abnormal hypercoagulable panel | 0.89 (0.35–2.24) | 0.80 |
| Sex | 0.88 (0.41–1.87) | 0.73 |
| Straight sinus thrombosis | 0.87 (0.27–2.85) | 0.82 |
| Headache | 0.81 (0.38–1.76) | 0.59 |
| Decreased visual acuity | 0.77 (0.26–2.23) | 0.62 |
| Unilateral transverse sinus thrombosis | 0.74 (0.34–1.62) | 0.46 |
| Cranial sixth nerve palsy | 0.69 (0.12–3.90) | 0.67 |
| Albumin | 0.48 (0.23–1.01) | 0.05 |
| Oral contraceptive pill use | 0.24 (0.03–1.93) | 0.18 |
CI, confidence interval; OR, odds ratio.
*
Statistically significant (p < 0.05).