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(A-B) Schematic illustration of the targeted theranostic platinum(IV) prodrug with a built-in AIE light-up apoptosis sensor for noninvasive in situ early evaluation of its therapeutic response. (C) Real-time CLSM images displaying the apoptotic progress of TPS-DEVD-Pt-cRGD-stained U87-MG cells. Reproduced with permission from 122, copyright 2014 American Chemical Society.
