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HER2(+) tumor surface-bound anti-HER2-C825 BsAb is rapidly internalized. Anti-HER2-C825 was radioiodinated and in vitro radiotracer binding studies were performed with HER2(+) BT-474 cells to determine the internalization and cellular processing at 37 °C of 131I-anti-HER2-C825. Data is presented as mean ± standard deviation (SD) (n = 3).
