Figure 2.

Synthesis and characteristics of PFTBA@HSA. (A) 'Unfolding self-assembly' method. Briefly, hydrophobic regions of albumin were first exposed by cutting off disulfide bonds followed by self-assembly with perfluorocarbons to form PFTBA@HSA nanoparticles. (B) PFTBA@HSA diameters detected via dynamic light scattering. (C) TEM images of PFTBA@HSA. (D) Stability of PFTBA@HSA mixed with different solutions: H₂O, PBS and plasma. (E) The oxygen release profile of O₂-adsorbed PFTBA@HSA under 1 atm. Data are shown as mean ± SD.