Table 2.
Clinicopathological characteristics of patient samples and expression of ACADL in ESCC and correlation between ACADL expression and clinicopathological characteristics of ESCC patients
| Characteristics | Total | ACADL
|
χ2 test P-value | Fisher’s exact test P-value | |
|---|---|---|---|---|---|
| Low expression 60.0% | High expression 40.0% | ||||
|
| |||||
| Gender | 0.283 | 0.186 | |||
| Female | 55 | 36 (65.5) | 19 (34.5) | ||
| Male | 80 | 45 (56.3) | 35 (43.7) | ||
| Age (years) | 0.058 | 0.079 | |||
| >60 | 69 | 36 (52.2) | 33 (47.8) | ||
| ≤60 | 66 | 45 (68.2) | 21 (31.8) | ||
| Clinical stage | <0.001 | <0.001 | |||
| I | 14 | 14 (100.0) | 0 (0.0) | ||
| II | 80 | 55 (68.8) | 25 (31.2) | ||
| III | 30 | 9 (30.0) | 21 (70.0) | ||
| IV | 11 | 3 (27.3) | 8 (72.7) | ||
| T classification | <0.001 | <0.001 | |||
| T1 | 16 | 15 (93.8) | 1 (6.2) | ||
| T2 | 52 | 38 (73.1) | 14 (26.9) | ||
| T3 | 52 | 25 (48.1) | 27 (51.9) | ||
| T4 | 15 | 3 (20.0) | 12 (80.0) | ||
| N classification | <0.001 | <0.001 | |||
| N0 | 91 | 67 (73.6) | 24 (26.4) | ||
| N1 | 44 | 14 (31.8) | 30 (68.2) | ||
| M classification | 0.021 | 0.027 | |||
| Yes | 11 | 3 (27.3) | 8 (72.7) | ||
| No | 124 | 78 (62.9) | 46 (37.1) | ||
| Histological differentiation | 0.003 | 0.003 | |||
| Well | 36 | 27 (75.0) | 9 (25.0) | ||
| Moderate | 74 | 46 (62.2) | 28 (37.8) | ||
| Poor | 25 | 8 (32.0) | 17 (68.0) | ||
| Status | <0.001 | <0.001 | |||
| Alive | 72 | 62 (86.1) | 10 (13.9) | ||
| Dead | 63 | 19 (30.2) | 44 (69.8) | ||
Abbreviations: ACADL, acyl-CoA dehydrogenase long chain; ESCC, esophageal squamous cell carcinoma.