Table 1.
IC50 values of NPB in a panel of carcinoma cell lines
| Tissue | Cell line | NPB IC50* ± SD, µM |
| Mammary | MCF10A† | NV |
| MCF12A† | NV | |
| MCF7 | 6.5 ± 1.06 | |
| T47D | 7.24 ± 1.91 | |
| BT474 | 5.31 ± 2.04 | |
| BT549 | 4.88 ± 1.31 | |
| MDA-MB-231 | 6.94 ± 1.86 | |
| Endometrial | Ishikawa | 7.51 ± 2.08 |
| ECC1 | 2.61 ± 0.97 | |
| RL95-2 | 6.38 ± 1.85 | |
| AN3 | 11.37 ± 2.61 | |
| Ovarian | SK-OV-3 | 7.34 ± 2.03 |
| OVCAR-2 | 4.21 ± 1.74 | |
| Caov-3 | 3.95 ± 0.93 | |
| HEY C2 | 6.82 ± 1.94 | |
| Ovca433 | 9.79 ± 2.48 | |
| Hepatocellular | #LO2 | NV |
| Hep3B | 6.94 ± 1.07 | |
| H2P | 4.18 ± 0.83 | |
| H2M | 5.57 ± 2.61 | |
| Colon | HCT116 | 7.29 ± 2.02 |
| DLD-1 | 2.46 ± 0.91 | |
| Caco-2 | 3.08 ± 0.76 | |
| Prostate | PC3 | 3.77 ± 1.51 |
| LNCaP | 8.02 ± 3.3 | |
| DU145 | 6.99 ± 1.72 | |
| Pancreatic | AsPC-1 | 3.83 ± 1.14 |
| BxPC-3 | 7.25 ± 2.09 |
Cell viability was measured using the AlamarBlue cell viability assay. NV, no value.
*
IC50 values were calculated using GraphPad Prism software (version 5.0).
†
Normal cells.