Table 4.

Enriched GO BPs (FDR < 5%) that overlap between platforms^®.

GOID	GO BP Term	Microarray				RNA-seq				TempO-seq
		Count	%	Pop Hits	FE	Count	%	Pop Hits	FE	Count	%	Pop Hits	FE
GO:0001666	Response to hypoxia	119	2.11	270	1.55	99	2.18	270	1.59	39	3.32	270	2.28
GO:0001731	Formation of translation preinitiation complex	17	0.30	24	2.50	18	0.40	24	3.24	9	0.77	24	5.92
GO:0001889	Liver development	85	1.51	145	2.07	81	1.78	145	2.42	32	2.72	145	3.48
GO:0006413	Translational initiation	32	0.57	52	2.17	29	0.64	52	2.41	13	1.11	52	3.95
GO:0006446	Regulation of translational initiation	19	0.34	31	2.16	17	0.37	31	2.37	12	1.02	31	6.11
GO:0006457	Protein folding	57	1.01	112	1.79	49	1.08	112	1.89	17	1.45	112	2.40
GO:0006629	Lipid metabolic process	44	0.78	89	1.74	42	0.93	89	2.04	17	1.45	89	3.01
GO:0006631	Fatty acid metabolic process	33	0.58	60	1.94	32	0.71	60	2.31	12	1.02	60	3.16
GO:0006635	Fatty acid beta-oxidation	35	0.62	46	2.68	31	0.68	46	2.92	23	1.96	46	7.89
GO:0006637	Acyl-coa metabolic process	19	0.34	28	2.39	16	0.35	28	2.47	9	0.77	28	5.07
GO:0006695	Cholesterol biosynthetic process	17	0.30	26	2.30	17	0.37	26	2.83	8	0.68	26	4.86
GO:0006749	Glutathione metabolic process	31	0.55	52	2.10	28	0.62	52	2.33	11	0.94	52	3.34
GO:0006915	Apoptotic process	157	2.78	366	1.51	120	2.64	366	1.42	41	3.49	366	1.77
GO:0006953	Acute-phase response	25	0.44	38	2.32	19	0.42	38	2.16	9	0.77	38	3.74
GO:0006979	Response to oxidative stress	76	1.35	146	1.83	61	1.34	146	1.81	22	1.87	146	2.38
GO:0007568	Aging	150	2.66	315	1.68	125	2.75	315	1.72	51	4.34	315	2.56
GO:0007584	Response to nutrient	69	1.22	137	1.77	59	1.30	137	1.86	19	1.62	137	2.19
GO:0007623	Circadian rhythm	52	0.92	121	1.51	46	1.01	121	1.64	18	1.53	121	2.35
GO:0009636	Response to toxic substance	65	1.15	119	1.92	61	1.34	119	2.22	30	2.55	119	3.98
GO:0009749	Response to glucose	54	0.96	106	1.80	47	1.04	106	1.92	18	1.53	106	2.68
GO:0010033	Response to organic substance	72	1.28	152	1.67	69	1.52	152	1.96	32	2.72	152	3.32
GO:0010243	Response to organonitrogen compound	35	0.62	68	1.81	34	0.75	68	2.16	14	1.19	68	3.25
GO:0014070	Response to organic cyclic compound	138	2.45	272	1.79	128	2.82	272	2.04	50	4.26	272	2.90
GO:0031100	Organ regeneration	45	0.80	91	1.74	39	0.86	91	1.85	22	1.87	91	3.82
GO:0031667	Response to nutrient levels	49	0.87	112	1.54	42	0.93	112	1.62	22	1.87	112	3.10
GO:0032355	Response to estradiol	91	1.61	201	1.60	81	1.78	201	1.74	40	3.40	201	3.14
GO:0032496	Response to lipopolysaccharide	114	2.02	280	1.43	101	2.23	280	1.56	39	3.32	280	2.20
GO:0032869	Cellular response to insulin stimulus	66	1.17	123	1.89	56	1.23	123	1.97	26	2.21	123	3.34
GO:0033539	Fatty acid beta-oxidation using acyl-coa dehydrogenase	16	0.28	19	2.97	15	0.33	19	3.42	9	0.77	19	7.48
GO:0042493	Response to drug	246	4.36	528	1.64	211	4.65	528	1.73	82	6.98	528	2.45
GO:0042542	Response to hydrogen peroxide	40	0.71	78	1.81	31	0.68	78	1.72	14	1.19	78	2.83
GO:0043065	Positive regulation of apoptotic process	133	2.36	338	1.39	115	2.53	338	1.47	53	4.51	338	2.47
GO:0043066	Negative regulation of apoptotic process	203	3.60	517	1.38	177	3.90	517	1.48	60	5.11	517	1.83
GO:0043434	Response to peptide hormone	63	1.12	129	1.72	51	1.12	129	1.71	19	1.62	129	2.32
GO:0045471	Response to ethanol	82	1.45	193	1.50	74	1.63	193	1.66	34	2.89	193	2.78
GO:0046686	Response to cadmium ion	27	0.48	45	2.11	22	0.48	45	2.12	12	1.02	45	4.21
GO:0051289	Protein homotetramerization	37	0.66	76	1.72	34	0.75	76	1.94	20	1.70	76	4.15
GO:0051301	Cell division	83	1.47	179	1.63	63	1.39	179	1.52	27	2.30	179	2.38
GO:0051384	Response to glucocorticoid	69	1.22	133	1.83	56	1.23	133	1.82	23	1.96	133	2.73
GO:0051603	Proteolysis involved in cellular protein catabolic process	28	0.50	51	1.93	24	0.53	51	2.04	11	0.94	51	3.40
GO:0055088	Lipid homeostasis	27	0.48	42	2.27	24	0.53	42	2.47	11	0.94	42	4.13
GO:0055114	Oxidation-reduction process	314	5.56	651	1.70	262	5.77	651	1.74	88	7.49	651	2.13
GO:0070542	Response to fatty acid	26	0.46	39	2.35	25	0.55	39	2.77	11	0.94	39	4.45
GO:0071407	Cellular response to organic cyclic compound	53	0.94	122	1.53	48	1.06	122	1.70	22	1.87	122	2.85
GO:0071456	Cellular response to hypoxia	57	1.01	137	1.47	49	1.08	137	1.55	22	1.87	137	2.53
GO:0097421	Liver regeneration	41	0.73	55	2.63	30	0.66	55	2.36	14	1.19	55	4.02
GO:0098609	Cell-cell adhesion	102	1.81	211	1.70	82	1.81	211	1.68	27	2.30	211	2.02
GO:1904871	Positive regulation of protein localization to Cajal body	8	0.14	8	3.52	8	0.18	8	4.33	6	0.51	8	11.84
GO:1904874	Positive regulation of telomerase RNA localization to Cajal body	13	0.23	15	3.05	12	0.26	15	3.46	8	0.68	15	8.42

^®Universe is 17,535. List totals: Microarray: 4,976; RNA-Seq: 4,053; TempO-Seq: 1,111. Enrichment performed using UniGene cluster IDs and the Database for Annotation, Visualization and Integrated Discovery (DAVID) v6.8.