Table 2. Inhibition Constants of Al–19F Complexes (14–17) for the Binding of [125I]IMPY to Aβ1–42 Aggregatesa.
| ligands | 14 | 15 | 16 | 17 | IMPY |
|---|---|---|---|---|---|
| n | 3 | 3 | 5 | 5 | |
| R | H | CH3 | H | CH3 | |
| Ki (nM)a | 124.1 ± 23.9 | 25.2 ± 1.9 | 40.9 ± 1.8 | 11.3 ± 0.74 | 4.6 ± 1.6 |
Measured in triplicate with results given as the mean ± standard deviation (SD).