Table 1.
Subject | Age, y | Sex | Viremiaa | Rashb | Day 28 PRNT60 | Day 42 PRNT60 | Day 180 PRNT60 |
---|---|---|---|---|---|---|---|
1 (Vaccine) | 19 | F | … | Days 12–20 | 54 | 70 | 30 |
2 (Vaccine) | 26 | F | … | … | 22 | 15 | <5 |
3 (Vaccine) | 25 | M | Days 8–9 | … | 52 | 106 | 22 |
4 (Vaccine) | 20 | M | Days 8–9 | Days 12–16 | 26 | 32 | <5 |
5 (Vaccine) | 20 | M | Day 6 | Days 12–20 | 33 | 19 | <5 |
6 (Vaccine) | 22 | M | … | … | <5 | <5 | <5 |
7 (Vaccine) | 19 | M | … | … | 18 | 8 | 8 |
8 (Vaccine) | 22 | F | Days 5–8 | Days 12–20 | 34 | 29 | 8 |
9 (Vaccine) | 19 | F | … | … | 25 | 33 | <5 |
10 (Vaccine) | 46 | F | … | Days 12–16 | 70 | 152 | 64 |
11 (Placebo) | 18 | F | … | … | <5 | <5 | <5 |
12 (Placebo) | 19 | M | … | … | <5 | <5 | <5 |
13 (Placebo) | 45 | M | … | … | <5 | <5 | <5 |
14 (Placebo) | 21 | F | … | … | <5 | <5 | <5 |
Abbreviations: F, female; M, male; PRNT60, reciprocal serum dilution providing 60% reduction in plaque formation.
aVirus detected in serum from tissue culture plaque formation assay.
bFirst and last day on which maculopapular rash was observed..