Table 2.
Human Papillomavirus (HPV) Prevalence in Urine Samples From 17-Year-Old Norwegian Girls, by Birth Cohort (N = 17749)
| HPV Type | Birth Cohorts Not Eligible for Routine HPV Vaccination | Birth Cohort Eligible for Routine HPV Vaccination | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Girls Born in 1994 (n = 5468) | Girls Born in 1996 (n = 5921) | Girls Born in 1997 (n = 6360) | |||||||
| No. | % (95% CI) | RR | No. | % (95% CI) | RR (95% CI) | No. | % (95% CI) | RR (95% CI) | |
| Any HPV type | 1087 | 19.9 (18.8–21.0) | 1 (ref) | 916 | 15.5 (14.6–16.4) | 0.78 (.72–.84) | 733 | 11.5 (10.8–12.3) | 0.58 (.53–.63) |
| Any HR typea | 611 | 11.2 (10.4–12.0) | 1 (ref) | 450 | 7.6 (7.0–8.3) | 0.68 (.61–.76) | 314 | 4.9 (4.4–5.5) | 0.44 (.39–.50) |
| Any probably/possibly HR typeb | 243 | 4.4 (3.9–5.0) | 1 (ref) | 239 | 4.0 (3.6–4.6) | 0.91 (.76–1.08) | 186 | 2.9 (2.5–3.4) | 0.66 (.55–.79) |
| Any LR typec | 597 | 10.9 (10.1–11.8) | 1 (ref) | 462 | 7.8 (7.1–8.5) | 0.71 (.64–.80) | 366 | 5.8 (5.2–6.4) | 0.53 (.47–.60) |
| Vaccine types | |||||||||
| Vaccine typesd | 403 | 7.4 (6.7–8.1) | 1 (ref) | 285 | 4.8 (4.3–5.4) | 0.65 (.56–.76) | 88 | 1.4 (1.1–1.7) | 0.19 (.15–.24) |
| HPV-16 or -18 | 280 | 5.1 (4.6–5.7) | 1 (ref) | 189 | 3.2 (2.8–3.7) | 0.62 (.52–.75) | 73 | 1.1 (.9–1.4) | 0.22 (.17–.29) |
| HPV-6 or -11 | 164 | 3.0 (2.6–3.5) | 1 (ref) | 121 | 2.0 (1.7–2.4) | 0.68 (.54–.86) | 20 | 0.3 (.2–.5) | 0.10 (.07–.17) |
| HPV-6 | 150 | 2.7 (2.3–3.2) | 1 (ref) | 104 | 1.8 (1.5–2.1) | 0.64 (.50–.82) | 17 | 0.3 (.2–.4) | 0.10 (.06–.16) |
| HPV-11 | 15 | 0.3 (.2–.5) | 1 (ref) | 17 | 0.3 (.2–.5) | 1.05 (.53–2.07) | 3 | 0.05 (.02–.1) | 0.17 (.05–.55) |
| HPV-16 | 192 | 3.5 (3.1–4.0) | 1 (ref) | 142 | 2.4 (2.0–2.8) | 0.68 (.55–.85) | 57 | 0.9 (.7–1.2) | 0.26 (.19–.34) |
| HPV-18 | 109 | 2.0 (1.7–2.4) | 1 (ref) | 61 | 1.0 (.8–1.3) | 0.52 (.38–.70) | 16 | 0.3 (.2–.4) | 0.13 (.08–.21) |
| Nonvaccine types | |||||||||
| Any nonvaccine HR type | 440 | 8.0 (7.4–8.8) | 1 (ref) | 330 | 5.6 (5.0–6.2) | 0.69 (.60–.79) | 256 | 4.0 (3.6–4.5) | 0.50 (.43–.58) |
| Any HR type other than 16, 18, 31, 33, and 45 | 370 | 6.8 (6.1–7.5) | 1 (ref) | 254 | 4.3 (3.8–4.8) | 0.63 (.54–.74) | 228 | 3.6 (3.2–4.1) | 0.53 (.45–.62) |
| HPV-31, -33, -45, -52, or -58 | 211 | 3.9 (3.4–4.4) | 1 (ref) | 176 | 3.0 (2.6–3.4) | 0.77 (.63–.94) | 98 | 1.5 (1.3–1.9) | 0.40 (.32–.51) |
| HPV-31, -33, or 45 | 141 | 2.6 (2.2–3.0) | 1 (ref) | 132 | 2.2 (1.9–2.6) | 0.86 (.68–1.09) | 57 | 0.9 (.7–1.2) | 0.35 (.26–.47) |
| HPV-31 | 69 | 1.3 (1.0–1.6) | 1 (ref) | 71 | 1.2 (1.0–1.5) | 0.95 (.68–1.32) | 15 | 0.2 (.1–.4) | 0.19 (.11–.32) |
| HPV-33 | 49 | 0.9 (.7–1.2) | 1 (ref) | 50 | 0.8 (.6–1.1) | 0.94 (.64–1.39) | 27 | 0.4 (.3–.6) | 0.47 (.30–.75) |
| HPV-35 | 11 | 0.2 (.1–.4) | 1 (ref) | 9 | 0.2 (.08–.3) | 0.76 (.32–1.77) | 16 | 0.3 (.2–.4) | 1.25 (.59–2.65) |
| HPV-39 | 71 | 1.3 (1.0–1.6) | 1 (ref) | 33 | 0.6 (.4–.8) | 0.43 (.29–.65) | 30 | 0.5 (.3–.7) | 0.36 (.24–.55) |
| HPV-45 | 30 | 0.5 (.4–.8) | 1 (ref) | 20 | 0.3 (.2–.5) | 0.62 (.35–1.07) | 17 | 0.3 (.2–.4) | 0.49 (.27–.87) |
| HPV-51 | 128 | 2.3 (2.0–2.8) | 1 (ref) | 76 | 1.3 (1.0–1.6) | 0.55 (.41–.73) | 73 | 1.1 (.9–1.4) | 0.49 (.37–.65) |
| HPV-52 | 72 | 1.3 (1.0–1.7) | 1 (ref) | 37 | 0.6 (.5–.8) | 0.47 (.32–.70) | 35 | 0.6 (.4–.8) | 0.42 (.28–.62) |
| HPV-56 | 65 | 1.2 (.9–1.5) | 1 (ref) | 56 | 0.9 (.7–1.2) | 0.80 (.56–1.13) | 58 | 0.9 (.7–1.2) | 0.77 (.54–1.09) |
| HPV-58 | 21 | 0.4 (.3–.6) | 1 (ref) | 15 | 0.3 (.2–.4) | 0.66 (.34–1.26) | 13 | 0.2 (.1–.3) | 0.53 (.27–1.05) |
| HPV-59 | 79 | 1.4 (1.2–1.8) | 1 (ref) | 68 | 1.1 (.9–1.5) | 0.79 (.58–1.10) | 48 | 0.8 (.6–1.0) | 0.52 (.37–.74) |
| Other | |||||||||
| Nonavalent HPV typese | 541 | 9.9 (9.1–10.7) | 1 (ref) | 409 | 6.9 (6.3–7.6) | 0.70 (.62–.79) | 179 | 2.8 (2.4–3.3) | 0.28 (.24–.34) |
Abbreviations: CI, confidence interval; HPV, human papillomavirus; HR, high risk; LR, low risk; RR, relative risk.
aHPV type 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, or 59.
bHPV type 26, 30, 53, 66, 67, 68, 69, 70, 73, or 82.
cHPV type 6, 11, 40, 42, 43, 54, 61, 74, 81, 83, 86, 87, 89, 90, or 91.
dHPV type 6, 11, 16, or 18.
eHPV type 6, 11, 16, 18, 31, 33, 45, 52, or 58.