Table 2.
Comparisons of blood flow velocities
| HC - OD | HC - OS | All MS eyes | MSNON eyes | MSON eyes |
P value | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| (20, eyes) | (20, eyes) | (38, eyes) | (25, eyes) | (13, eyes) | (OD vs. OS in HCs) | (All MS vs. HCs) | (MSNON vs. HCs) | (MSON vs. HCs) | (MSON vs. MSNON) | |
| Arterioles, mm/s; mean (SD) | 3.95 (0.59) | 4.08 (0.60) | 3.51 (0.81) | 3.48 (0.88) | 3.59 (0.69) | 0.1a | 0.01 b | 0.009 b | 0.046 b | 0.42b |
| Venules, mm/s; mean (SD) | 3.11 (0.46) | 3.23 (0.52) | 2.76 (0.50) | 2.75 (0.53) | 2.80 (0.45) | 0.064a | 0.003 b | 0.005 b | 0.048 b | 0.48b |
HC = healthy control; OD = right; OS = left; MS = multiple sclerosis; MSNON = multiple sclerosis without optic neuritis; MSON = multiple sclerosis with optic neuritis; SD = standard deviation
aPaired t-test
bMixed-effects linear regression adjusted for age, sex, and within-subject inter-eye correlations in HCs (as well as disease duration between the MS groups)
P ≤ 0.05 indicates significance