Table 3.
Adjusted Odds Ratios and Estimates for Primary and Secondary Outcomes
| Characteristic | Level | Post-op Hyperglycemia (72 h) | Post-op Hyperglycemia (24 h) | ||
|---|---|---|---|---|---|
| Odds Ratio (95% CI) | P-value | Odds Ratio (95% CI) | P-value | ||
| Dexamethasone | Yes – No | 3.07 (2.34, 4.03) | < 0.001* | 4.03 (2.44, 6.65) | < 0.001* |
| Use | |||||
| Medical | THA – TKA | 1.09 (0.83, 1.42) | 0.540 | 1.67 (1.01, 2.76) | 0.046* |
| Procedure | THA – UKA | 1.53 (0.93, 2.51) | 0.100 | 1.96 (0.90, 4.33) | 0.092 |
| Diabetes type | Type I – Type II | 1.89 (1.20, 3.00) | 0.006* | 0.98 (0.36, 2.68) | 0.969 |
| Diabetic | Oral hyperglycemic – | 3.89 (2.07, 7.31) | < 0.001* | 2.53 (0.97, 6.61) | 0.058 |
| Medication | None | 7.96 (4.20, 15.09) | < 0.001* | 5.37 (1.99, 14.44) | 0.001* |
| Insulin Aa– None | 10.65 (5.14, 22.10) | < 0.001* | 8.77 (2.61, 29.52) | 0.001* | |
| Insulin Bb– None | |||||
| Gender | Female – Male | 1.23 (0.94, 1.60) | 0.126 | 1.34 (0.82, 2.20) | 0.242 |
| Age | One unit increase | 1.01 (1.00, 1.02) | 0.226 | 1.02 (1.00, 1.05) | 0.051 |
| BMI | One unit increase | 1.00 (0.97, 1.02) | 0.615 | 1.00 (0.96, 1.05) | 0.871 |
| Pre-Op HgbA1c | One unit increase | 1.38 (1.23, 1.54) | < 0.001* | 1.26 (1.03, 1.52) | 0.022* |
| Post-op Hyperglycemia by Dose (72 h) | |||||
| Dexamethasone | Yes – No | ||||
| Use | 4,5, or 8 mg – No | 1.75 (1.04, 2.94) | 0.034* | ||
| 10 mg – 4,5, or 8 mg | 2.01 (1.18, 3.42) | 0.010* | |||
| 10 mg – No | 3.52 (2.64, 4.71) | < 0.001* | |||
*P-value < 0.05
a< 0.6 units/kg/day or 80 units/day
b> 0.6 units/kg/day or 80 units/day