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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Nano Res. 2018 May 8;11(9):4890–4904. doi: 10.1007/s12274-018-2078-9

Figure 4.

Figure 4

DLS measurement, in vitro CD105 targeting, chelator-free 89Zr labeling, and elution profile of UCNP@[89Zr]HMSN-PEG5k-TRC105. (a) Size distribution of UCNP@HMSN-PEG5k-TRC105 measured by DLS. (b) Flow cytometry analysis of fluorescein-conjugated UCNP@HMSN-PEG5k-TRC105 (50 nM, 30 min incubation) in HUVECs (CD105-positive). (c) 89Zr labeling yields of UCNP@HMSN at varying temperatures in solutions of different pH values. (d) A PD-10 elution profile of UCNP@[89Zr]HMSN-PEG5k-TRC105. PBS was used as the mobile phase.