Table 4.
Peptide | E. coli BL21 DE3 | Staph aureus 6835p | Staph epidermidis | P. aeruginosa 103 | P. aeruginosa 01 |
---|---|---|---|---|---|
CM15 | 7.6 | 7.6 | 7.6 | 0.48 | 0.95 |
D1,13 | 5.4 | 2.7 | 5.4 | 0.34 | 0.34 |
D3,13 | 19 | 19 | 39 | 4.8 | 2.4 |
D3,14 | 5.2 | 2.6 | 42 | 10 | 5.2 |
D3,7,13 | 12 | 12 | 24 | 3 | 3 |
D3,7,14 | * | 2 | 31 | 7.9 | 3.9 |
Selectivity indices were calculated by dividing the LD50 for RAW264.7 macrophages by the MIC for each respective bacterial strain. Higher values indicate greater antimicrobial selectivity.
Not calculated due to low antimicrobial activity (MIC > 128 μM).