Molecular graphics images of HI18 in complex with IAPP. Polar interactions between the flexible N-termini enhance nonpolar interactions between IAPP and HI18, extending the hydrophobic surface shown in orange (β-wrapin subunit 1), red (β-wrapin subunit 2), cyan and blue (IAPP) surface representation, of the antiparallel β-sheet in the structure. β-Wrapin subunits 1 and 2 are shown in red and orange tube representation, respectively, and IAPP is shown in cyan and blue tube representation. Red and blue labels indicate residues of subunit 1 of the β-wrapin and IAPP, respectively. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)