Skip to main content
. Author manuscript; available in PMC: 2019 Jun 25.
Published in final edited form as: Neonatology. 2018 Jun 25;114(3):242–250. doi: 10.1159/000489387

Fig. 1.

Fig. 1.

Form of immunoglobulins (Ig) secreted into human milk by plasma cells. IgA is mainly secreted as a dimer IgA joined by the J-chain polypeptide and contains alpha heavy constant chains; IgG is secreted as a monomer (without a J-chain) and possesses gamma heavy constant chains; IgM is secreted as a pentamer joined by the J-chain and contains mu heavy constant chains. All Igs contain at least two light constant chains (kappa-chain or lambda-chain), two light variable region chains and two heavy variable region chains, which form the specific antigen binding site.