Table 2.
Association With Survival to Hospital Discharge
| Survival to Hospital Dischargea | OR(95%CI) | ||||
|---|---|---|---|---|---|
| Factor | No (n = 179) | Yes (n = 113) | P Value | Unadjusted | Adjusted |
| Any hypotension | |||||
| 0–6 h | 58 (32.4) | 20(17.7) | .006b | 0.45 (0.25–0.80) | 0.39 (0.20–0.74) |
| 0–72 h | 99 (55.3) | 62 (54.9) | .94b | 0.98(0.61–1.58) | NA |
| Age at randomization, median (IQ.R), y | 1.3 (0.3–7.2) | 3.1 (1.0–9.8) | <.001c | 1.05 (1.01–1.09) | NA |
| Sex | |||||
| Male | 112 (62.6) | 82 (72.6) | .08b | 1 [Reference] | NA |
| Female | 67 (37.4) | 31 (27.4) | 0.63 (0.38–1.05) | NA | |
| Cardiac arrest witnessed | |||||
| No | 116 (64.8) | 54 (47.8) | 1 [Reference] | 1 [Reference] | |
| Yes | 52 (29.1) | 56 (49.6) | .001b | 2.31 (1.41–3.80) | 2.04(1.15–3.61) |
| Unable to determine | 11 (6.1) | 3 (2.7) | 0.59 (0.16–2.19) | 0.46 (0.12–1.84) | |
| Chest compressions administered by bystander | |||||
| No | 62 (34.6) | 35 (31.0) | .81b | 1 [Reference] | NA |
| Yes | 110(61.5) | 73 (64.6) | 1.18 (0.71–1.96) | NA | |
| Unable to determine | 7 (3.9) | 5 (4.4) | 1.27 (0.37–4.29) | NA | |
| Initial cardiac arrest rhythm noted by EMS or hospital | |||||
| Asystole | 117 (65.4) | 55 (48.7) | .01b | 1 [Reference] | NA |
| Bradycardia | 9 (5.0) | 10 (8.8) | 2.36 (0.91–6.15) | NA | |
| PEA | 26 (14.5) | 16 (14.2) | 1.31 (0.65–2.64) | NA | |
| Ventricular fibrillation or tachycardia | 8 (4.5) | 15 (13.3) | 3.99 (1.60–9.97) | NA | |
| Unknown | 19 (10.6) | 17(15.0) | 1.90 (0.92–3.94) | NA | |
| Estimated duration of chest compressions | |||||
| ≤15 min | 28 (15.6) | 38 (33.6) | <.001b | 1 [Reference] | 1 [Reference] |
| >15to≤30min | 61 (34.1) | 48 (42.5) | 0.58(0.31–1.08) | 0.57 (0.30–1.10) | |
| >30min | 83 (46.4) | 23 (20.4) | 0.20 (0.10–0.40) | 0.21 (0.10–0.42) | |
| Unable to determine | 7 (3.9) | 4 (3.5) | 0.42 (0.11–1.58) | 0.57(0.14–2.27) | |
| Primary cause of cardiac arrest | |||||
| Cardiac | 15 (8.4) | 22(19.5) | .02b | 1 [Reference] | NA |
| Respiratory | 134 (74.9) | 77 (68.1) | 0.39 (0.19–0.80) | NA | |
| Other | 5(2.8) | 5 (4.4) | 0.68(0.17–2.77) | NA | |
| Unknown | 25 (14.0) | 9 (8.0) | 0.25 (0.09–0.67) | NA | |
| Treatment received | |||||
| Hypothermia | 87 (48.6) | 66 (58.4) | .10b | 1 [Reference] | NA |
| Normothermia | 92 (51.4) | 47 (41.6) | 0.67 (0.42–1.08) | NA | |
| Preexisting condition | 77 (43.0) | 65(57.5) | .02b | 1.79(1.11–2.89) | 1.75 (1.01–3.04) |
| Night or weekend arrest | 91 (50.8) | 50 (44.2) | .27b | 0.77 (0.48–1.23) | NA |
Abbreviations: EMS, emergency medical services; IQR, interquartile range; NA, not applicable; OR, odds ratio; PEA, pulseless electrical activity.
a
Percentages have been rounded and may not total 100. All variables were considered for entry into logistic regression model using forward stepwise selection.
b
Calculated using the χ2 test of no association.
c
Calculated using the Wilcoxon rank sum test.