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. Author manuscript; available in PMC: 2019 Oct 22.
Published in final edited form as: JACC Cardiovasc Interv. 2018 Sep 26;11(20):2072–2080. doi: 10.1016/j.jcin.2018.07.004

Table 3.

Association between Severe Endothelial Dysfunction and Low Wall Shear Stress using Logistic Regression Analysis with Generalized Estimating Equations to Account for Within-Subject Correlations.

Odds Ratio Estimate (95%CI) p-value Odds Ratio Estimate (95%CI) p-value
Age 1.02 (0.98 – 1.05) 0.30 0.99 (0.96 – 1.03) 0.80
Females 2.39 (1.00 – 5.71) 0.51 2.44 (1.04 – 5.72) 0.04
African American 0.84 (0.35 – 2.02) 0.70 0.80 (0.38 – 2.12) 0.80
Hypertension 1.19 (0.48 – 2.97) 0.71 1.33 (0.45 –3.94) 0.60
Diabetes Mellitus 4.44 (2.84 – 6.93) < 0.001 5.01 (1.57 – 16.01) 0.007
Active Smoker 1.27 (0.46 – 3.49) 0.64 1.41 (0.37 – 5.44) 0.62
Hyperlipidemia 1.23 (0.51 – 2.96) 0.64 1.40 (0.58 – 3.38) 0.46
Wall Shear Stress (<1 Pa vs. ≥1 Pa) 8.42 (4.07 – 17.42) < 0.001 9.14 (2.60–32.11) < 0.001