Figure 5.

Gene set enrichment analysis vs T2 map lipid area. A, Representative raw (left) and segmented (right) T2 map derived from in vivo carotid magnetic resonance imaging (MRI). %Lipid-rich necrotic core (LRNC) calculated as segmented T2 map lipid area/total plaque cross-sectional area. B, An illustration of one of the most enriched pathways (Morserle IFN [interferon]-α response, C2 collection, Molecular Signatures Database) as plaque lipid content increases (P<0.01; false discovery rate [FDR], <0.25). *Lumen.