Table 1.
Characteristics of the cohort
| Total study cohort (n = 44) | 18F-Flut (+) (n = 18) | 18F-Flut (–) (n = 26) | p-value (18F-Flut(+) versus 18F-Flut(–)) | |
| Age, y | 65.91 (6.88) | 68.17 (4.80) | 64.35 (7.72) | 0.070a |
| Women, n (%) | 25 (56.8) | 10 (55.56) | 15 (57.69) | 0.890b |
| MMSE, points | 28.53 (1.52) | 28.06 (1.89) | 28.85 (1.16) | 0.208c |
| CSF Aβ42 (pg/ml) | 873.57 (320.04) | 567.19 (167.31) | 1062.12 (232.67) | <0.001a |
| WMH volume (mm3) | 5850.50 (7235.81) | 7280.00 (9372.94) | 4860.85 (5274.92) | 0.448a,d |
Values are given in mean (standard deviation). Statistically significant differences shown in bold. aIndependent-samples T-test. bPearson Chi-square test. cMann-Whitney U test. dp-value for log transformed WMH volume adjusted for age. 18F-Flut, 18F-Flutemetamol; MMSE, Mini-Mental State Examination; CSF, cerebrospinal fluid; Aβ, amyloid β-peptide; WMH, white matter hyperintensities.