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. 2018 Oct 24;2(1):169–179. doi: 10.3233/ADR-180078

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Fig. 1. — Metabolic stability of P8 in mouse and human plasma (A) and brain (B). P8 (1μM) was added to mouse (closed circles) and human (open circles) plasma or brain extract and the reactions were incubated at room temperature for up to 4 h. The amount of P8 remaining was determined by LC/MS/MS and is presented as a percentage of the sample at time 0.