Skip to main content
. 2018 Oct 24;2(1):169–179. doi: 10.3233/ADR-180078

Fig. 3.

Fig. 3.

Mean (±SD) concentrations (ng/ml) of P8 in plasma (A) and CSF (B) of rats following a single IV, IN, or SC dose administration. P8 in PBS (11 mg/kg for IV and SC and 5.5 mg/kg for IN) was delivered to rats (n = 6 per dose group). Blood and CSF samples were removed for up to 180 mins from the onset of administration and analyzed by HPLC as described. PK analysis was performed using standard non-compartmental analysis models in Phoenix WinNonlin (v. 6.3). Black circles: IV administration; Open circles: IN administration; Triangles: SC administration.