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. Author manuscript; available in PMC: 2018 Nov 5.
Published in final edited form as: Pediatrics. 2018 Apr 4;141(5):e20173006. doi: 10.1542/peds.2017-3006

TABLE 3.

Association Between Sex, Uropathogen, Etiology of Neurogenic Bladder, and Leukocyte Esterase

Predictors Cultures ≥ 10 000 CFU/mL Cultures ≥ 100 000 CFU/mL
Odds of Leukocyte Esterase Greater Than Trace 95% CI Odds of Leukocyte Esterase Greater Than Trace 95% CI
Sex
 Female Reference Reference
 Male 1.44a (1.16–1.80)a 1.33a (1.15 – 1.80)a
Uropathogen
 E coli Ref Ref
 P aeruginosa 1.53 (0.97 – 2.51) 1.74 (0.96 – 3.35)
 S saprophyticus 1.56 (0.22 – 31.07) b
 Enterococcus species 0.63a (0.47 – 0.86)a 0.45a (0.31 – 0.64)a
 Klebsiella species 0.84 (0.61 – 1.16) 0.94 (0.66 – 1.34)
 Proteus species 3.14a (1.67 – 6.60)a 3.40a (1.68 – 7.85)a
 Enterobacter species 1.04 (0.63 – 1.77) 0.84 (0.50 – 1.42)
 Other 0.97 (0.73 – 1.28) 1.20 (0.86 – 1.68)
Etiology of neurogenic bladder
 Myelomeningocele Reference Reference
 Anorectal malformation 1.33 (0.92 – 1.94) 1.32 (0.86 – 2.09)
 Tethered cord 1.19 (0.81 – 1.75) 1.53 (0.97 – 2.46)
 Bladder exstrophy 1.03 (0.49 – 2.41) 2.28 (0.83 – 8.06)
 Cloacal malformation 1.49a (1.01 – 2.25)a 1.85a (1.10 – 3.24)a
 Spinal cord injury 0.41a (0.18 – 0.97)a 1.12 (0.50 – 2.62)
 Eagle-Barrett syndrome 1.95 (0.64 – 8.45) 2.62 (0.47 – 49.49)
 Other 1.19 (0.94 – 1.50) 1.11 (0.86 – 1.45)
Presence of mitrofanoff 1.80a (1.40 – 2.31)a 1.93a (1.42 – 2.66)a
Presence of hydronephrosis 1.06 (0.55 – 2.17) 1.23 (0.56 – 3.02)
Presence of VUR 2.32a (1.77 – 3.07)a 3.25a (2.33 – 4.62)a

—, not applicable.

a

Indicates statistical significance.

b

Unable to be computed because of a small sample size.