Table 3.
ROC Analysis with removal of UTC patients with positive nitrites and pyuria
| Predictor | AUC | Cut-off value | Sensitivity (%) | Specificity (%) | Positive predictive value (%) | Negative predictive value (%) | Positive likelihood ratio | Negative likelihood ratio | |
|---|---|---|---|---|---|---|---|---|---|
| Diagnosis of UTI versus no UTI | |||||||||
| UTC with nitrites and no pyuria removed | uNGAL (pg/g crt) | 0.92 (0.86–0.97) | 817 | 86 | 89 | 49 | 98 | 7.8 | 0.2 |
| uNGAL (ng/mL) | 0.92 (0.87–0.96) | 229 | 91 | 84 | 41 | 99 | 5.7 | 0.1 | |
| All UTC with nitrites removed | uNGAL (pg/g crt) | 0.92 (0.87–0.97) | 816 | 86 | 90 | 56 | 98 | 8.6 | 0.2 |
| uNGAL (ng/mL) | 0.94 (0.81–0.97) | 229 | 91 | 87 | 51 | 98 | 7.0 | 0.1 | |
| Diagnosis of UTI versus UTC | |||||||||
| UTC with nitrites and no pyuria removed | uNGAL (pg/g crt) | 0.87 (0.79–0.96) | 817 | 86 | 81 | 57 | 95 | 4.5 | 0.3 |
| uNGAL (ng/mL) | 0.87 (0.79–0.95) | 229 | 91 | 78 | 55 | 97 | 4.1 | 0.1 | |
| All UTC with nitrites removed | uNGAL (pg/g crt) | 0.88 (0.80–0.97) | 816 | 86 | 82 | 67 | 93 | 4.8 | 0.2 |
| uNGAL (ng/rnl) | 0.92 (0.85–0.98) | 229 | 91 | 84 | 71 | 96 | 5.7 | 0.1 | |
AUC area under the curve, ROC receiver operator characteristic, uNGAL urine neutrophil gelatinase-associated lipocalin