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. Author manuscript; available in PMC: 2018 Nov 5.
Published in final edited form as: Clin Sci (Lond). 2018 Jul 31;132(14):1615–1627. doi: 10.1042/CS20180398

Figure 2.

Figure 2.

Pharmacological inhibition of ASK1 attenuates mitogen-induced cell growth. ASM cells either from COPD patients (A-C) or non-COPD (D-F) were treated with either 10% FBS (A, D). PDGF (B, E), or EGF (C, F). After 72h fluorescence was measured to assess the increase in DNA content as a measure of cell growth. Results are expressed as mean ± SEM. 4–6 patient samples were used in each treatment group. Data were analyzed by one-way ANOVA followed by Bonferroni’s multiple comparison test (*p<0.05, **p<0.01).