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. 2018 Oct 23;25(4):988–1001. doi: 10.1016/j.celrep.2018.09.067

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© 2018 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Early Dysregulation of MEF-to-iN Conversion in the Absence of KMT2B

(A) Correlation of fold changes in Kmt2b^−/− across PSA-NCAM⁻ and PSA-NCAM⁺ cells. All tested genes are plotted.

(B) Heatmap of expression across normal transdifferentiation (left) and on day 13 (right) of DEGs with genome-wide significance in both cell fractions and also significantly differentially expressed during normal transdifferentiation. Z scores were calculated separately for the left and right portions of the heatmap.