Table 4.
In vivo pharmacokinetic parameters of 23 in mice.
| Pharmacokinetic Parameters of 23 in C57BL/6 Mice (3 mg/kg) | ||
|---|---|---|
| Route | IV | PO |
| AUC0→∞ (hr●ng/mL) | 3220 | 782 |
| t1/2 (h) | 3.5 | 4.3 |
| Cmax (ng/mL) | 67 | |
| CL (mL/min/kg) | 16 | |
| Vdss (L/kg) | 4.6 | |
| %F | 24 | |
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.