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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Pharmacol Res. 2018 Sep 13;136:140–150. doi: 10.1016/j.phrs.2018.09.007

Figure 1: Pharmacokinetic (Cmax)/Pharmacodynamic (First-in-Morning Cortisol Level) Analysis after 14 Days of Daily Vamorolone Therapy.

Figure 1:

Blood samples were drawn in the morning pre-dose after 2 weeks of daily vamorolone therapy. Each dot represents an individual patient. Adrenal suppression is defined as a first-morning cortisol of <3.6 μg/dL [100 nmol/L] (represented by the orange line). Dot colors depict dose levels (purple = 6.0; green= 2.0; dark blue = 0.75; red= 0.25 mg/kg).