Table 3.
Correlations between walking capacity, rsFC values, and covariates (n = 119)
| 6MWT | MLR–SFG/ACC connectivity | MLR–cerebelulm connectivity | CLR–M1F connectivity | |
|---|---|---|---|---|
| 6MWT distance | 1 | 0.33 (<0.001) | 0.37 (<0.001) | −0.28 (0.002) |
| rsFC: MLR–SFG/ACC (BnS 12) | 0.33 (<0.001) | 1 | 0.01 (0.944) | −0.20 (0.027) |
| rsFC: MLR–cerebellum (BnS 253) | 0.37 (<0.001) | 0.01 (0.944) | 1 | −0.34 (<0.001) |
| rsFC: CLR–M1F (BnS 67) | −0.28 (0.002) | −0.20 (0.027) | −0.34 (<0.001) | 1 |
| No. fMRI motion outlier volumes | 0.16 (0.078) | −0.05 (0.611) | 0.28 (0.002) | 0.07 (0.473) |
| Mean fMRI framewise displacement | 0.01 (0.953) | 0.07 (0.445) | 0.13 (0.166) | 0.09 (0.315) |
| Age | −0.13 (0.144) | 0.02 (0.795) | −0.14 (0.119) | 0.00 (0.979) |
| Male sex | 0.01 (0.905) | −0.03 (0.735) | −0.03 (0.787) | 0.02 (0.813) |
| Height | 0.12 (0.177) | 0.05 (0.587) | 0.04 (0.659) | 0.07 (0.470) |
| Body mass index | −0.05 (0.600) | 0.01 (0.939) | 0.05 (0.627) | −0.16 (0.082) |
| Resting heart rate | −0.27 (0.003) | −0.20 (0.026) | −0.11 (0.235) | 0.12 (0.205) |
| Resting systolic blood pressure | −0.22 (0.018) | −0.09 (0.325) | −0.10 (0.256) | 0.09 (0.313) |
| Dyspnea rating | −0.09 (0.334) | 0.04 (0.669) | −0.03 (0.741) | −0.05 (0.580) |
| Depression score (BDI) | −0.16 (0.088) | −0.03 (0.716) | −0.19 (0.038) | 0.28 (0.002) |
| Visuoconstructional ability (WASI‐BD) | −0.06 (0.491) | −0.08 (0.386) | −0.24 (0.009) | 0.10 (0.266) |
rsFC = resting‐state functional connectivity; 6MWT = 6‐min walk test; MLR = midbrain locomotor region; SFG = superior frontal gyrus; ACC = anterior cingulate cortex; CLR = cerebellar locomotor region; M1F = primary motor cortex foot area; BDI = Beck Depression Inventory II; WASI‐BD = Wechsler abbreviated scale of intelligence ‐ block design.
Values are Pearson r (p value).