Table 2.
Physiological Stress, Psychological Stress and Outcomes by Implant Strategy
| Overall | Implant Strategy | ||||
|---|---|---|---|---|---|
| (n=44) Mean± SD | (n=44) Median (IQR) | BTT (n = 24) Median(IQR) | DT (n = 20) Median(IQR) | Mann-Whitney U or Chi2 p-value | |
| Physiological Stress: Biomarkers | |||||
| Cortisol (μg/dL) | |||||
| Waking | 0.26 ± 0.12 | 0.23 (.19–.33) | 0.21 (.16–.25) | 0.29 (.21–.38) | 0.03 |
| 30 minute after waking | 0.31 ± 0.18 | 0.30 (.19–.42) | 0.29 (.19–.40) | 0.30 (.21–.46) | 0.55 |
| Bedtime | 0.12 ± 0.11 | 0.08 (.05–.13) | 0.08 (.05–.11) | 0.10 (.05–.18) | 0.37 |
| Area under the curve | 322.3 ± 226 | 263.7 (179–419) | 253.7 (181–363) | 271.5 (176–470) | 0.45 |
| C-reactive protein (pg/mL) | 1196 ± 823 | 1003.6 (479–1654) | 1329.9 (306–2135) | 980.6 (518–1433) | 0.63 |
| Physiological Stress: Sleep Quality | |||||
| Global sleep quality (0 = best - 21 = worst) | 6.2 ± 3.5 | 5.5 (3–8.5) | 6 (3–8) | 5 (3.5–9.5) | 0.81 |
| Psychological Stress | |||||
| Perceived Stress Scale (0 = no stress – 40 = maximum) | 11.8 ± 7.0 | 12 (6–18) | 12 (6–17) | 11.5 (6–18) | 0.93 |
| Depression PHQ-9 (0 = No symptoms – 10 = maximum depressive symptoms) | 3.4 ± 3.8 | 2 (1–5) | 2 (.5–4) | 2.5 (1–5.5) | 0.46 |
| Fatigue MAF total (1 = no fatigue – 50 = severe fatigue) | 15.1 ± 8.7 | 16.6 (11–21) | 18.5 (11–21) | 14.3 (12–20) | 0.46 |
| Quality of Life | |||||
| KCCQ Overall (0 = poor – 100 = excellent QOL) | 73.0 ± 13.5 | 74.6 (66–82) | 75.6 (66–82) | 71.0 (65–81) | 0.44 |
| Hi QOL (>75) %(n) | 48% (21) | 50% (12) | 45% (9) | 0.74 | |
| Functional Status | |||||
| 6 Minute Walk Test Distance (meters) | 337.9 ± 162 | 368.1 (275–440) | 367.3 (274–432) | 374.9 (278–453) | 0.87 |
| Hi 6MWT (>300m) %(n) | - | 68%(30) | 67% (16) | 70% (14) | 0.81 |