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. 2018 Aug 4;39(12):4733–4742. doi: 10.1002/hbm.24318

Figure 3.

Figure 3

Lateralization index LI = (L − H)/(L + H) where L refers to activation in the left hemisphere and R refers to the activation in the right hemisphere. Threshold‐independent LI (ThI LI) is calculated from the integrated Z‐score weighted distributions of all active voxels, and threshold‐dependent LI (ThD LI) is obtained using the integrated weighted distribution of 50% AMPLE (activation mapping as a percentage of local excitation) suprathreshold voxels in Z‐score activation maps. Hemispheric dominance for language function is determined by the LI values—left hemispheric dominance indicates LI ≥ 0.2, right hemispheric dominance indicates LI ≤ −0.2 and bilateral/mixed dominance indicates that −0.2 < LI < 0.2. ThI LI and ThD LI values from both sessions of sentence completion (SC) and silent word generation (SWG) language activation maps for holohemispheric and local regions of interest (ROIs) that is, expressive (Exp), receptive (Rec), Broca's area (BA), and Wernicke's area (WA) across the entire right‐handed patient population included in this study are displayed below. Each subject ThI LI or ThD LI value is depicted as an individual “x” or “o” symbol respectively in this plot