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. 2018 Nov 5;8:16320. doi: 10.1038/s41598-018-34557-7

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Exosomes increase miR-486-5p levels in kidney cortex, proximal tubules, glomeruli and kidney endothelial cells. Depicted are results for real-time PCR of miR-486-5p in renal cortex, medulla and whole kidney (a) dissected proximal tubules and glomeruli (b) and isolated kidney endothelial cells (c) Sham (untreated mice), IR (mice with 30 min of bilateral kidney ischemia) and IR+EX (mice with 30 min of bilateral kidney ischemia followed by infusion of 20 μg of exosomes). *P < 0.05 vs IR, ⁺P < 0.005 vs IR by one-way ANOVA, n = 4 for each panel.