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. 2018 Nov 5;8:16361. doi: 10.1038/s41598-018-34513-5

Table 2.

Relative toxicity of five insecticides to two strains of S. zeamais [i.e., the pyrethroids susceptible (SzSusc) and pyrethroid resistant (SzPyrSel) strains] and two strains of S. oryzae (i.e., SoPyrTol and SoPyrR).

Insecticide Sitophilus strains No. of insects LD50 (95% FI) mg a.i/kg of grains LD95 (95% FI) mg a.i/kg of grains RR50 (95% CL) RRa50 (95% CL) Χ 2 P
Deltamethrin SzSusc 493 0.68 (0.5–0.9) 1.6 (1.2–2.8) * * 7.42 0.09
SzPyrSel (—) (—) (—) (>2500) (>2500) (—) (—)
SoPyrTol 490 25.95 (23.1–28.5) 82.5 (69.3–106.7) * 37.6 (35.1–40.3) 2.20 0.53
SoPyrR 495 69.39 (64.2–76.0) 201.8 (159.8–291.5) 2.7 (2.4–2.9) 101.0 (91.2–110.9) 1.54 0.67
Lambda-Cyhalothrin SzSusc 526 0.71 (0.7–0.8) 1.5 (1.3–1.7) * * 4.31 0.23
SzPyrSel (—) (—) (—) (—) (—) (—) (—)
SoPyrTol 596 12.06 (10.1–13.9) 54.4(45.3–69.1) * 16.9 (15.9–18.0) 1.57 0.81
SoPyrR 588 174.3 (146.1–219.6) 1243.1(973.4–2259.0) 14.5 (9.8–21.2) 244.6 (167.5–357.3) 4.46 0.61
Indoxacarb SzSusc 689 0.40 (0.3–0.5) 5.2 (3.9–7.4) * * 6.77 0.24
SzPyrSel 599 3.79 (3.1–4.5) 15.3 (12.9–19.1) 9.5 (7.8–11.5) 9.5 (7.8–11.5) 1.67 0.80
SoPyrTol 496 3.05 (2.6–3.5) 11.2 (9.3–14.2) * 7.6 (6.3–9.6) 1.06 0.78
SoPyrR 512 1.55 (1.2–1.9) 14.2 (10.6–20.5) 0.5 (0.5–0.6) 3.9 (3.2–4.8) 4.72 0.45
Imidacloprid SzSusc 617 1.21 (0.9–1.7) 13.0 (6.6–41.9) * * 3.82 0.43
SzPyrSel 496 0.83 (0.7–3.4) 15.5 (9.60–18.3) 0.7 (0.5–1.1) 0.7 (0.5–1.1) 5.63 0.13
SoPyrTol 398 1.32 (0.2–5.2) 14.2 (8.50–19.4) * 1.1 (0.17–2.3) 1.40 0.49
SoPyrR 450 1.54 (0.5–4.1) 16.6 (11.2–25.1) 1.2 (0.6–5.1) 1.3 (0.27–2.1) 1.34 0.85
Thiamethoxam SzSusc 497 0.68 (0.6–0.8) 2.6 (2.1–3.7) * * 2.79 0.43
SzPyrSel 404 1.46 (1.1–2.0) 15.6 (8.4–41.9) 2.2 (1.7–2.8) 2.2 (1.7–2.8) 2.21 0.33
SoPyrTol 597 1.95 (1.5–2.9) 25.3 (11.9–90.9) * 2.9 (1.9–4.2) 4.10 0.39
SoPyrR 449 0.94 (0.69–1.2) 12.8 (7.3–38.2) 0.48 (0.3–0.7) 1.4 (1.1–1.7) 3.12 0.53
Spinosad SzSusc 635 15.7 (14.5–16.9) 37.3 (32.5–45.5) * * 7.36 0.12
SzPyrSel 522 23.6 (21.2–27.3) 80.2 (57.9–141.6) 1.5 (1.2–1.8) 1.5 (1.2–1.8) 6.07 0.11
SoPyrTol 499 17.2 (13.8–20.7) 80.5 (64.6–107.5) * 1.1 (0.7–1.3) 1.88 0.59
SoPyrR 512 21.5 (19.3–26.6) 76.1 (69.7–82.4) 1.25 (0.9–8.3) 1.3 (1.2–1.7) 4.28 0.34

FI = Fiducial Intervals; RR50 = Resistance ratio determined by LD50 of given population/LD50 of most susceptible population (*); RRa50 = Resistance ratio determined by LD50 of given population/LD50 of SzSusc; 95% CL = 95% Confidence limits; χ2 = Chi-square for lack-of-fit to the probit model, and P = Probability associated with the chi-square statistic. (—) Data not available as no dose-response curve could be computed for the selected population SzPyrSel.