Table 2.
Circadian rhythmicity of mean arterial pressure (MAP) and renal oxygenation (pO2) during angiotensin II (AngII) infusion.
| MESOR Con | MESOR AngII | Amplitude Con | Amplitude AngII | Acrophase Con (ZT h) | Acrophase AngII (ZT h) | |
|---|---|---|---|---|---|---|
| Oxygenation Cortex (%, N = 6) | 100.0 (99.3–100.7) | 100.0 (99.4–100.6) | 5.8 (4.7–6.8) | 3.6 (2.6–4.6)* | 16.9 (16.3–17.4) | 18.8 (17.2–20.5) |
| Oxygenation Medulla (%, N = 7) | 100.0 (98.8–101.2) | 100.0 (98.9–101.1) | 4.9 (3.6–6.3) | 3.5 (2.0–4.9) | 16.9 (16.0–17.7) | 19.4 (17.5–21.4) |
| MAP (mmHg, N = 5) | 95.5 (94.6–95.8) | 145.4 (141.8–149.1) | 1.6 (0.8–2.4) | 5.5 (0.3–10.6) | 18.9 (17.6–20.2) | 14.1 (11.7–16.4)* |
Data were analyzed by cosinor analysis (period = 24 h), lighting schedule; lights-on at 6am (ZT0), and lights-off at 6 pm (ZT12). MESOR: Circadian rhythm-adjusted mean, Acrophase: Peak time of cosine function. (median, 95% CI), *p < 0.05 vs. Control data obtained from Emans et al. 2017.