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. 2018 Oct 30;12:775. doi: 10.3389/fnins.2018.00775

FIGURE 6.

FIGURE 6

Response characteristics of SRD neurons to different intensities of EA during CRD. (A–F) Representative examples showing a decrease in discharges of SRD neurons during the CRD + EA sequence was elicited by EA at 2–8 mA. The upper rows show the unit discharges at different stimulations and the lower rows show these discharges in histogram. Note: CRD (Colorectal distention), CRD + EA (CRD plus EA). (G) This histogram shows that CRD induced discharges of SRD neurons were inhibited by EA at 2–8 mA. Data consists of the average spikes per second (mean ± SEM). ∗p < 0.05 compared with CRD; #p < 0.05 compared with 0.5 mA EA; +p < 0.05 compared with 1 mA EA. (H) This stimulus–response curve shows the percentage of inhibition induced by EA. A positive linear relationship between intensity and inhibition percentage of inhibition was observed within 2–6 mA (Y = 10.79 log X + 3.387, P < 0.001). Further increased the intensity to 8 mA induced a significant decrease in inhibition percentage.