Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Oct 30;10:33. doi: 10.3389/fnsyn.2018.00033

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Cheng, Song and Augustine.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Changes in mEPSC frequency produced by optogenetic elevation of presynaptic cAMP levels. (A) Time course of normalized mEPSC frequency in response to illumination (470 nm light, 30 s at blue bar) of a TWT neuron expressing opto-β2-AR. Red points indicate mEPSC frequency, normalized to baseline values, measured following the start of the light flash. Smooth curve indicates an exponential fit to the decay of mEPSC frequency following the end of the light flash. (B) Same for a TKO neuron expressing opto-β2-AR. Open symbols indicate normalized mEPSC frequency measured following the start of the light flash. (C) Mean increase in mEPSC frequency produced by activation of opto-β2-AR in WT (black) and TKO (white) neurons. Error bars indicate ±SEM, while asterisks indicate significant differences.