Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Process for Evaluating a GWAS Locus
Many approaches exist for identifying mechanisms at GWAS loci. In this review, we address three major questions at GWAS loci: (1) How many association signals exist at a locus? (2) What are the candidate causal variant(s)? (3) What are the target gene(s)? This flowchart shows how an accumulation of evidence can address these questions.
