Table 1.

Characteristics of patient and control groups.

	Controls	mHE	HE
N (f/m)	15 (5/10)	5 (2/3)	6 (1/5) [9 (2/7)]
Age (y; median (first, third quartile))	65.0 (52.0, 69.8)	57.0 (46.0, 71.3)	64.5 (58.0, 75.0) [66.0 (60.8, 76)]]
CFF (Hz; median (first, third quartile))	42.6 (40.5, 43.3)	39.5 (37.6, 40.3)	36.7 (34.7, 37.9) [37.1 (34.7, 37.9)]
Stimulation amplitude (mA, median (first, third quartile))	3.2 (3.0, 4.2))	2.3 (2.0, 3.3)	3.4 (2.8, 3.8) [3.3 (2.7, 3.9)]
Etiology of cirrhosis	–	4 ALC, 1 overlap	4 ALC, 1NASH, 1 HCV, 1 CRYP, 1 NT, 1 AI

Data are presented for those participants that entered the main analyses (see Figures 2, 3) because their behavioral data could be successfully fitted (see Supplementary Figure S2). The column HE shows additionally (in square brackets []) the data for all patients that successfully completed the task, e.g., including three patients that did not enter the main analyses due to non-successful fits (see Supplementary Figures S1, S2C). mHE, minimal hepatic encephalopathy; HE, manifest hepatic encephalopathy; CFF, critical flicker frequency; ALC, alcoholic; Overlap, overlap syndrome; NASH, non-alcoholic steatohepatitis; HCV, hepatitis C virus; CRYP, cryptogenic, NT, nutritive toxic; AI, autoimmune hepatitis.