Table 2.
MRI-derived indices of cardiac function extracted at rest and following the infusion of dobutamine.
| Rest | Dobutamine | p | |
|---|---|---|---|
| HR (beats/min) | 66 ± 9 (55–82) | 105 ± 19 (76–127) | 0.008* |
| CO (l/min) | 5.6 ± 1(4.3–7.2) | 9.2 ± 1.7 (7.2–11.6) | 0.008* |
| SBP (mmHg) | 115.5 ± 12.8 (98–137) | 139.2 ± 19.9 (119–186) | 0.013* |
| MAP (mmHg) | 86.4 ± 10.2 (76.2–102.3) | 98.3 ± 11 (87.1–117.8) | 0.066 |
| DBP (mmHg) | 66 ± 10.3 (56–85) | 63.7 ± 8.1 (53–77) | 0.48 |
| LVESV (mL) | 70.3 ± 18.9 (45.4–103.6) | 48.9 ± 24 (19–88.2) | 0.015* |
| LVEDV (mL) | 153.5 ± 27.9 (123.3–199.7) | 141.8 ± 41.5 (81–217.5) | 0.17 |
| SV (mL) | 85.4 ± 14 (70.3–108.8) | 88.9 ± 17.8 (59–118.5) | 0.51 |
| EF (%) | 56 ± 8 (47–71) | 65 ± 10 (53–82) | 0.066 |
| SVR (mmHg·s/mL) | 0.97 ± 0.23 (0.69–1.46) | 0.66 ± 0.14 (0.46–0.9) | 0.008* |
| CT (mL/mmHg) | 1.9 ± 0.52 (1.2–2.8) | 2.1 ± 0.41 (1.3–2.6) | 0.37 |
Values are presented as mean ± standard deviation, with ranges given in parentheses. HR, heart rate; CO, cardiac output; SBP, systolic blood pressure; MAP, mean arterial pressure; DBP, diastolic blood pressure; LVESV, left ventricular end-systolic volume; LVEDV, left ventricular end-diastolic volume; SV, stroke volume; EF, ejection fraction; SVR, systemic vascular resistance; CT, total systemic arterial compliance.
*
p < 0.05 vs. rest.