Table 1.
Minimal inhibitory concentration (MIC) values determined by colorimetric assay (resazurin) and minimal bactericidal concentrations (MBC) determined by conventional plating method on E. coli.
|
Escherichia coli | ||||||||
|---|---|---|---|---|---|---|---|---|
| Peptide/Antibiotics | PMB |
STM |
NCR247 |
NCR335 |
||||
| MIC | MBC | MIC | MBC | MIC | MBC | MIC | MBC | |
| MHB | 0.5 μM | 1 μM | 16 μM | 64 μM | 128 μM | 128 μM | 64 μM | 128 μM |
| MHBII | 0.5 μM | 0.5 μM | 8 μM | 32 μM | 128 μM | 128 μM | 64 μM | 128 μM |
| LSM | 0.5 μM | 1 μM | 1 μM | 2 μM | 16 μM | 32 μM | 16 μM | 16 μM |
MIC and MBC values were determined for the NCR247 and NCR335 peptides and for PMB and STM using a standard, validated method in MHB, MHBII and LSM media.