Table 2.
Reason for exclusion.
| No. | Study | Reason for exclusion | No. | Study | Reason for exclusion |
|---|---|---|---|---|---|
| 1 | Singh A et al., 2014 [34] | Only one patient | 17 | Cook DC et al., 2013 [35] | Not comparing a synthetic bone substitute |
| 2 | Coathup MJ et al., 2015 [36] | Treatment not for alveolar bone | 18 | Menezes LM et al., 2012 [37] | Not comparing a synthetic bone substitute |
| 3 | Kato E et al., 2015 [38] | Outcome measure not related to alveolar bone regeneration | 19 | Horvarth A et al., 2013 [39] | Not comparing a synthetic bone substitute |
| 4 | Gupta G et al., 2014 [40] | Not comparing a synthetic bone substitute | 20 | Ghanaati S et al., 2013 [25] | Control group not available |
| 5 | Troedan A et al., 2014 [41] | Outcome measure not related to alveolar bone regeneration | 21 | Pietruska M et al., 2012 [42] | Outcome measure not related to alveolar bone regeneration |
| 6 | Reichert C et al., 2014 [43] | Outcome measure not related to alveolar bone regeneration | 22 | Emam H et al., 2011 [44] | Not comparing a synthetic bone substitute and control group not available |
| 7 | Cosso MG et al., 2014 [3] | Not comparing a synthetic bone substitute | 23 | Lee CY et al., 2011 [45] | Not comparing a synthetic bone substitute |
| 8 | Ghanaati S et al., 2014 [46] | Outcome measure not related to alveolar bone regeneration | 24 | Mairoana C et al., 2011 [47] | Not comparing a synthetic bone substitute and control group not available |
| 9 | de Ruiter A et al., 2014 [4] | Control group not available | 25 | Caubet J et al., 2011 [48] | Control group not available |
| 10 | Traini T et al., 2015 [49] | Control group not available | 26 | Goene RJ et al., 2007 [50] | Outcome measure not related to alveolar bone regeneration |
| 11 | Gupta S et al., 2013 [51] | Not comparing a synthetic bone substitute | 27 | Pappalardo S et al., 2005 [52] | Only one patient |
| 12 | Cannizaro G et al., 2013 [53] | Outcome measure not related to alveolar bone regeneration | 28 | Nemcovsky CE et al., 2001 [54] | Not comparing a synthetic bone substitute |
| 13 | Peres MF et al., 2013 [55] | Not comparing a synthetic bone substitute | 29 | Fugazzotto PA et al., 1999 [56] | Only one patient |
| 14 | Pieri F et al, 2013 [57] | Control group not available | 30 | Wheeler SL et al., 1996 [58] | Not comparing a synthetic bone substitute |
| 15 | Kim DM et al., 2013 [59] | Not comparing a synthetic bone substitute | 31 | Galgut PN et al., 1992 [60] | Outcome measure not related to alveolar bone regeneration |
| 16 | Corinaldesi G et al., 2013 [61] | Not comparing a synthetic bone substitute | 32 | Hurzeler MB et al., 1996 [62] | Outcome measure not related to alveolar bone regeneration |