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. 2018 Nov 2;4(10):e00867. doi: 10.1016/j.heliyon.2018.e00867

Fig. 13.

Fig. 13

Disaggregation of RHO gene inside Disease to Genes Network A). Selection of RHO gene inside network. B) Expanding selection of RHO-RP5 genes complex to its closest neighbors C) Subtracting all nodes related to RHO gene from the network. This 3-step process shows the importance of RHO gene inside the network, since once RHO gene is selected RP5 gene automatically is selected with it, suggesting and not previously noted relationship. When the RPO-RP5 complex is subtracted a great portion of the network is disassembled, suggesting his importance as a biological hub.