Skip to main content
. 2018 Oct 30;9:2439. doi: 10.3389/fimmu.2018.02439

Figure 8.

Figure 8

Comparison of histopathological changes in lungs among different regimens. The immunization and challenge schedules were shown in Figures 2A,D,G. Arrowheads indicate AF positive bacteria. HE, scale bar = 400 μm; AF staining, scale bar = 50 μm. (A) The representative lung pathological changes of three CTT3H-based vaccines alone immunized C57BL/6 mice against primary M. tuberculosis infection and (B) lung pathological scores (n = 3). (C) The representative lung pathological changes of BCG prime-CTT3H-based boosters in mice against primary infection and (D) lung pathological scores (n = 3). (E) The representative lung pathological changes of BCG prime-CTT3H-based boosters against mice late persistent TB infection and (F) lung pathological scores (n = 3).