eTable. Staging of breast implant-associated anaplastic large-cell lymphoma (BIA-ALCL).
| Tumor extent (T) | T1 | T2 | T3 | T4 |
| Confined to seroma or a layer on luminal side of capsule | Early capsule infiltration | Cell aggregates or sheets infiltrating the capsule | Lymphoma infiltrates beyond the capsule | |
| Lymph nodes (N) | N0 | N1 | N2 | |
| No lymph node involvement | One regional lymph node positive | Multiple regional lymph nodes positive | ||
| Metastases (M) | M0 | M1 | ||
| No distant spread | Spread to other organs/distant sites | |||
| Stage: | Frequency: | |||
| IA | T(1)N(0)M(0) | 35.6% | ||
| IB | T(2)N(0)M(0) | 11.5% | ||
| IC | T(3)N(0)M(0) | 13.8% | ||
| IIA | T(4)N(0)M(0) | 25.3% | ||
| IIB | T(1–3)N(1)M(0) | 4.6% | ||
| III | T(4)N(1–2)M(0) | 9.2% | ||
| IV | T(any)N(any)M(1) | 0% | ||
Data modified from Clemens et al. J Clin Oncol 2016; 34: 160–8 (9)