Table 1.
Demographic and clinical characteristics of EOCAD patients and controls.
| Variable | EOCAD (n = 1093) | Control (n = 1117) | P value |
|---|---|---|---|
| Gender, male n (%)# | 986 (90.21) | 1015 (90.86) | 0.597 |
| Age, years∗ | 43.90 ± 4.61 | 43.83 ± 4.52 | 0.693 |
| BMI (kg/m2)∗ | 26.78 ± 3.61 | 24.75 ± 3.38 | <0.001 |
| Hypertension, n (%)# | 314 (28.73) | 305 (27.31) | 0.578 |
| Diabetes, n (%)# | 214 (19.58) | 46 (4.12) | <0.001 |
| Smoking, n (%)# | 533 (48.76) | 446 (41.72) | <0.001 |
| Drinking, n (%)# | 677 (61.94) | 415 (39.92) | <0.001 |
| FBG, mmol/l∗ | 6.06 ± 2.57 | 5.43 ± 1.63 | <0.001 |
| TG, mmol/l∗ | 2.15 ± 1.84 | 1.45 ± 1.13 | <0.001 |
| TC, mmol/l∗ | 4.54 ± 1.29 | 4.52 ± 1.96 | 0.635 |
| HDL-C, mmol/l∗ | 1.08 ± 0.27 | 1.27 ± 0.33 | <0.001 |
| LDL-C, mmol/l∗ | 2.62 ± 0.99 | 2.51 ± 0.74 | 0.004 |
| Lp(a), mmol/l∗ | 287.89 ± 331.77 | 205.65 ± 218.89 | <0.001 |
| SCr, μmol/l∗ | 73.33 ± 15.86 | 75.14 ± 13.81 | 0.139 |
| UA, μmol/l∗ | 5.843 ± 1.479 | 5.433 ± 1.529 | <0.001 |
| Male, μmol/l∗ | 5.965 ± 1.442 | 5.560 ± 1.492 | <0.001 |
| Female, μmol/l∗ | 4.718 ± 1.343 | 4.178 ± 1.311 | 0.004 |
| Myocardial infarction, n (%) | 633 (57.91) | — | — |
| 1-vessel disease, n (%) | 326 (51.50) | — | — |
| 2-vessel disease, n (%) | 199 (31.44) | — | — |
| 3-vessel disease, n (%) | 108 (17.06) | — | — |
EOCAD: early-onset coronary artery disease; BMI: body mass index; FBG: fasting blood glucose; TG: triglyceride; TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; Lp (a): lipoprotein (a); SCr: serum creatinine; UA: uric acid. ∗Continuous variables are expressed as mean ± SD. The P value of the continuous variables was calculated by the unpaired t-test. #Categorical variables are expressed as percentages. The P value of the categorical variables was calculated by χ2 test.