Table 4.
Association of serum uric acid categories and Gensini score in male and female EOCAD patients.
| Variable | Male EOCAD patients | Female EOCAD patients | ||||
|---|---|---|---|---|---|---|
| Normouricemia (<7.0 mg/dl) | Hyperuricemia (≥7.0 mg/dl) | P value∗ | Normouricemia (<6.0 mg/dl) | Hyperuricemia (≥6.0 mg/dl) | P value∗ | |
| Number, n | 764 | 222 | — | 82 | 24 | — |
| Age, years | 43.74 ± 4.55 | 43.40 ± 1.99 | 0.333 | 46.18 ± 3.59 | 45.18 ± 3.06 | 0.379 |
| BMI | 26.59 ± 3.54 | 27.86 ± 3.65 | <0.001 | 25.94 ± 3.52 | 25.98 ± 4.07 | 0.967 |
| FBG, mmol/l | 6.07 ± 2.53 | 5.72 ± 2.06 | 0.067 | 6.59 ± 3.29 | 8.04 ± 5.11 | 0.197 |
| TG, mmol/l | 2.01 ± 1.53 | 2.78 ± 2.49 | <0.000 | 1.83 ± 2.10 | 1.63 ± 0.50 | 0.744 |
| TC, mmol/l | 4.52 ± 1.27 | 4.65 ± 1.38 | 0.170 | 4.45 ± 1.17 | 4.40 ± 2.36 | 0.953 |
| HDL-C, mmol/l | 1.07 ± 0.26 | 1.03 ± 0.25 | 0.057 | 1.21 ± 0.29 | 1.04 ± 0.23 | 0.042 |
| LDL-C, mmol/l | 2.64 ± 0.97 | 2.59 ± 1.02 | 0.586 | 2.45 ± 0.86 | 2.69 ± 1.93 | 0.686 |
| Lp(a), mmol/l | 289.96 ± 344.69 | 262.95 ± 281.29 | 0.286 | 331.47 ± 345.69 | 257.07 ± 193.18 | 0.486 |
| SCr, μmol/l | 85.71 ± 14.80 | 92.55 ± 15.89 | <0.001 | 69.65 ± 14.31 | 77.48 ± 13.46 | 0.017 |
| Gensini score | 48.25 ± 37.23 | 56.33 ± 45.80 | 0.017 | 26.22 ± 22.50 | 71.77 ± 64.33 | 0.044 |
EOCAD: early-onset coronary artery disease; BMI: body mass index; FBG: fasting blood glucose; TG: triglyceride; TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; Lp (a): lipoprotein (a); SCr: serum creatinine; UA: uric acid. ∗Continuous variables are expressed as mean ± SD. The P value of the continuous variables was calculated by unpaired t-test.